Insights with impact

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Man With Beaker

The biology of roginolisib: Activity without immune toxicity

Catherine Pickering

End of year reflections from our CEO

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Driving breakthroughs for myelofibrosis care

Lars Van Der Veen

What’s next for cambritaxestat?

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Realizing the potential of PI3Kδ inhibitors in peripheral T-cell lymphomas

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iOnctura expands roginolisib trials to the US

Catherine Pickering

iOnctura enhances board to accelerate growth and innovation

Michael Lahn 819x1024

Addressing drug resistance in non-small cell lung cancer

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Scientific innovation in uveal melanoma

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Opportunities and challenges in oncology immunotherapy

Catherine Pickering

Reflections from our CEO

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Pancreatic cancer – our commitment to scientific advances

Giusy di Conza

A bold new era in global cancer drug discovery

Catherine Pickering

A note from our CEO

Giusy Di Conza Comp 2

Realising the potential of autotaxin therapy in cancer

Pexels Thirdman 7659470

PI3Kδ inhibitors offer serious promise in solid tumors

Michael Lahn 819x1024

Emerging therapies offer hope for uveal melanoma patients

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Testing new taxonomy – do not send

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Testing MailPoet on a back-dated article please ignore for the moment

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Testing MailPoet on a back-dated article please ignore for the moment – Take 2

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The PI3Kδ inhibitor roginolisib (IOA-244) preserves T-cell function and activity

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iOnctura CEO to present at the 2026 J.P. Morgan Healthcare Conference

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Drug Discovery World – Autotaxin inhibition: unlocking new frontiers in cancers and beyond

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The selective PI3Kδ inhibitor roginolisib synergizes with ruxolitinib against progenitor cells from naïve and JAKi-refractory/resistant patients with myelofibrosis

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Roginolisib (IOA-244), an orally bioavailable, selective PI3Kδ inhibitor, in combination with venetoclax and rituximab in patients with relapsed chronic lymphocytic leukemia (CLL)

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PlaΤform: A multicenter, multi-arm, academic platform trial evaluating novel agents and combinations in relapsed or refractory peripheral T-cell lymphomas

Data & Publications Bg

Trial in progress: A study of roginolisib in combination with ruxolitinib in patients with myelofibrosis who are unresponsive to JAK inhibitors (HEMA-MED)

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Drug Discovery World – ASH 2025: Combined focus on myelofibrosis

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iOnctura initiates Phase I/II trial in patients with myelofibrosis ahead of new non-clinical data at ASH

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